Table of Contents

Pregabalin withdrawal symptoms

Pregabalin, the ultimately famous drug, has so many uses, in so many different diseases.

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It is used in relieving nerve pain, some types of seizures, in addition to other anticonvulsants in the treatment of partial-onset seizures, neuropathic pain associated with diabetes or spinal cord injury, treatment of fibromyalgia, postherpetic neuralgia.

Pregabalin may be also used off-label for generalized anxiety disorder, hot flashes, restless leg syndrome (the urge to move your legs, it usually happens during the night), and social anxiety disorder.

But Pregabalin is not always that good, inappropriately taking Pregabalin may cause Pregabalin withdrawal symptoms when trying to stop it.

Always use Pregabalin exactly as described by your physician to take the ultimate benefit from it, and avoid the risks.

What is Pregabalin?

Pregabalin is a prescription need drug that is available in many dosage forms, capsules, solutions, and extended-release tablets.

All the dosage forms of Pregabalin are taken orally, not available as neither injection nor rectal forms.

How does it work?

It is used in epilepsy by reducing the abnormal electrical activity in the brain.
It also blocks pain by interfering with the messages of pain moving through the brain and down the spine that’s how it is used in nerve pain.
In treating anxiety, Pregabalin stops the brain from releasing the chemicals responsible for the feeling of anxiety.

Pregabalin withdrawal symptoms

Dosage:

To avoid suffering from Pregabalin withdrawal symptoms, you must follow the directions of your physician strictly.

The dose is usually based on age, weight, and medical condition.

The dose may always be modified by your physician according to the response to treatment.

Pediatrics

For the treatment of partial-onset seizures:

Extended-release tablets are not used in pediatrics, with regular capsules and oral solutions only.

It is used in patients older than 1-month-old.

From 1 month – 17 years old:

Starting dose: 3.5 mg/kg/day taken orally in divided doses every 8 hours from 1 month – 4 years or every 8-12 hours for those older than 4 years old.

Maintenance dose: The dose may be increased weekly till it reaches 10 mg/kg/day.

Maximum dose: The dose not to exceed 600 mg/day.

Older than 17 years old:

Starting dose: 150 mg/day taken orally in divided doses every 8-12 hours.

Maintenance dose: The dose may be increased daily, but not to exceed 600 mg/day.

The use in children with renal impairment has not been studied.

Adults

For the treatment of the neuropathic pain caused by diabetes:

Regular-release capsules

Starting dose: 50 mg orally every 8 hours

Maintenance dose: The dose may be increased to 100 mg orally every 8 hours within 1 week if needed, but not to exceed 300 mg/day.

Extended-release tablets

Starting dose: 165 mg orally per day

Maintenance dose: the dose may be increased to 330 mg orally per day within 1 week, and it is the maximum dose allowed.

For the treatment of postherpetic neuralgia:

Regular-release tablets

Starting dose: 150-300 mg/day orally divided every 8-12 hours

Maintenance dose: The dose may be increased to 300 mg/day divided every 8-12 hours after 1 week if needed.

Extended-release tablets

Starting dose: 165 mg orally per day

Maintenance dose: The dose may be increased to 330 mg orally per day within 1 week, and it the maximum dose allowed

For the treatment of fibromyalgia:

It is treated using regular-release capsules and oral solution only.

Starting dose: 75 mg orally every 12 hours

Maintenance dose: The dose may be increased to 150 mg every 12 hours after 1 week if needed.

Maximum dose: 300-400 mg/day

For the treatment of partial-onset seizures:

It is used as adjunctive therapy using regular-release capsules and oral solution only.

Starting dose: 150 mg/day orally divided every 8-12 hours

Maximum dose: 600 mg/day

For the treatment of neuropathic pain caused by an injury to the spinal cord:

It is treated using regular-release capsules and oral solution only.

Starting dose: 75 mg orally every 12 hours

Maintenance dose: The dose may be increased to 300 mg/day orally divided every 12 hours

If tolerance occurred the dose may be increased to 600 mg/day divided every 12 hours

Stopping Pregabalin suddenly may cause withdrawal symptoms; the dose should be decreased gradually.

Your doctor will tapper the dose for you to avoid pregabalin withdrawal symptoms.