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Amoxicillin is an antibiotic used to treat a number of bacterial infections.^[3] These include middle ear infection, strep throat, pneumonia, skin infections, and urinary tract infections among others.^[3] It is taken by mouth, or less commonly by injection.^[3][4]

Common adverse effects include nausea and rash.^[3] It may also increase the risk of yeast infections and, when used in combination with clavulanic acid, diarrhea.^[5] It should not be used in those who are allergic to penicillin.^[3] While usable in those with kidney problems, the dose may need to be decreased.^[3] Its use in pregnancy and breastfeeding does not appear to be harmful.^[3] Amoxicillin is in the beta-lactam family of antibiotics.^[3]

Amoxicillin was discovered in 1958 and came into medical use in 1972.^[6][7] It is on the World Health Organization’s List of Essential Medicines, the safest and most effective medicines needed in a health system.^[8] It is one of the most commonly prescribed antibiotics in children.^[9] Amoxicillin is available as a generic medication.^[3] It has a wholesale cost in the developing world of between US$0.02 and $0.05 per pill.^[10] In the United States, ten days of treatment costs about US$16 ($0.40 per pill).^[3] In 2016, it was the 28th most prescribed medication in the United States, with more than 28 million prescriptions