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Furosemide, sold under the brand name Lasix among others, is a medication used to treat fluid build-up due to heart failure, liver scarring, or kidney disease.[1] It may also be used for the treatment of high blood pressure.[1] It can be taken by injection into a vein or by mouth.[1] When taken by mouth, it typically begins working within an hour, while intravenously, it typically begins working within five minutes.[1]

Common side effects include feeling lightheaded with standing, ringing in the ears, and sensitivity to light.[1] Potentially serious side effects include electrolyte abnormalities, low blood pressure, and hearing loss.[1] Blood tests are recommended regularly for those on treatment.[1] Furosemide is a type of loop diuretic that works by decreasing the reabsorption of sodium by the kidneys.[1]

Furosemide was patented in 1959 and approved for medical use in 1964.[2] It is on the World Health Organization’s List of Essential Medicines, the safest and most effective medicines needed in a health system.[3] The wholesale price in the developing world is between US$0.004 and US$0.02 per day.[4] In the United States, it is available as a generic medication and costs about US$0.15 per day.[1] In 2016, it was the 15th most prescribed medication in the United States, with more than 32 million prescriptions.[5] It is on the World Anti-Doping Agency‘s banned drug list due to concerns that it may mask other drugs.[6] It has also been used in race horses for the treatment and prevention of exercise-induced pulmonary