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Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that typically produces a calming effect. It is commonly used to treat a range of conditions including anxiety, alcohol withdrawal syndrome, benzodiazepine withdrawal syndrome, muscle spasms, seizures, trouble sleeping, and restless legs syndrome. It may also be used to cause memory loss during certain medical procedures.  It can be taken by mouth, inserted into the rectum, injected into a muscle, or injected into a vein.  When given into a vein, effects begin in one to five minutes and last up to an hour. By mouth, effects may take 40 minutes to begin.

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Diazepam tablets (2, 5, and 10 mg)

Diazepam is mainly used to treat anxiety, insomnia, panic attacks and symptoms of acute alcohol withdrawal. It is also used as a premedication for inducing sedation, anxiolysis, or amnesia before certain medical procedures (e.g., endoscopy). Diazepam is the drug of choice for treating benzodiazepine dependence with its long half-life allowing easier dose reduction. Benzodiazepines have relatively low toxicity in overdose

Diazepam has a number of uses including:

  • Treatment of anxiety, panic attacks, and states of agitation
  • Treatment of neurovegetative symptoms associated with vertigo
  • Treatment of the symptoms of alcohol, opiate, and benzodiazepine withdrawal
  • Short-term treatment of insomnia
  • Treatment of muscle spasms
  • Treatment of tetanus, together with other measures of intensive treatment
  • Adjunctive treatment of spastic muscular paresis (paraplegia/tetraplegia) caused by cerebral or spinal cord conditions such as stroke, multiple sclerosis, or spinal cord injury (long-term treatment is coupled with other rehabilitative measures)
  • Palliative treatment of stiff person syndrome
  • Pre- or postoperative sedation, anxiolysis or amnesia (e.g., before endoscopic or surgical procedures)
  • Treatment of complications with a hallucinogen crisis and stimulant overdoses and psychosis, such as LSD, cocaine, or methamphetamine
  • Preventative treatment of oxygen toxicity during hyperbaric oxygen therapy
  • Dosages should be determined on an individual basis, depending on the condition being treated, the severity of symptoms, patient body weight, and any other conditions the person may have.