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Anafranil

depression
Clomipramine 25mg (Brand)
Novartis
60Tablets52 €Buy Now
Clomipramine 75mg SR
(Brand) Novartis
60Tablets52 €Buy Now

Seroxat (Paxil)

Paroxetine 20mg (Brand)
GSK
100Tablets152 €Buy Now

Prozac (Brand) Sarafem

Fluoxetine 20mg (Brand)
Lilly
112CapsDepression173 €Buy Now

Prozac (Generic)

Fluoxetine 20mg (Generic)120CapsDepression95 €Buy Now

Cipram (Generic)

Citalopram 20mg
(Generic)
140TabletsDepression109 €Buy Now

Clomipramine, sold under the brand name Anafranil among others, is a tricyclic antidepressant (TCA).[4] It is used for the treatment of obsessive–compulsive disorder, panic disorder, major depressive disorder, and chronic pain.[4] It may decrease the risk of suicide in those over the age of 65.[4] It is taken by mouth.[4]

Common side effects include dry mouth, constipation, loss of appetite, sleepiness, weight gain, sexual dysfunction, and trouble urinating.[4] Serious side effects include an increased risk of suicidal behavior in those under the age of 25, seizures, mania, and liver problems.[4] If stopped suddenly a withdrawal syndrome may occur with headaches, sweating, and dizziness.[4] It is unclear if it is safe for use in pregnancy.[4] Its mechanism of action is not entirely clear but is believed to involve increased levels of serotonin.[4]

Clomipramine was discovered in 1964 by the Swiss drug manufacturer Ciba-Geigy.[5] It is on the World Health Organization’s List of Essential Medicines, the safest and most effective medicines needed in a health system.[6] It is available as a generic medication.[4] The wholesale price in the developing world is between 0.11 and 0.21 per day as of 2014.[7] In the United States the wholesale costs as of 2018 is about US$9 per day.[8] It was made from imipramine

Clomipramine has a number of uses in medicine including in the treatment of: